Pinealon

Pinealon is a synthetic tripeptide (Glu-Asp-Arg) originally developed in Russia as part of short peptide bioregulator research.
It is thought to mimic or influence natural peptide signaling in the brain, with studies suggesting potential roles in neuroprotection,
cognitive function, and anti-aging. Pinealon is sometimes referred to as a “cognitive peptide” due to its effects in preclinical research.
It remains experimental and is not FDA-approved for therapeutic use.

How It Is Used in Research Settings

• Investigated for improving memory and learning in aging and cognitive decline models.
• Studied for neuroprotective effects in oxidative stress and hypoxia research.
• Explored for supporting recovery in stroke, traumatic brain injury, and neurodegenerative disease models.
• Examined for anti-aging potential through effects on gene expression and neuronal survival.

Proposed Uses (Research Areas)

• Cognitive function and memory studies.
• Neurodegenerative disease models (Alzheimer’s, Parkinson’s).
• Stroke and traumatic brain injury research.
• Aging and longevity studies.

How It Is Dosed in Research Settings

• Injectable (Subcutaneous or Intramuscular): Studied at doses of 100–200 mcg daily in animal and limited human models.
• Oral: Some research formulations explore oral capsules, though peptide bioavailability via this route remains uncertain.
• Cycle length: Protocols vary from short-term (10–20 days) to repeated annual or semi-annual courses in aging research studies.
• Handling: Supplied as lyophilized powder; reconstituted with bacteriostatic water and stored refrigerated.

Important Considerations

• Regulatory status: Pinealon is not FDA-approved; most research originates from Russia and Eastern Europe.
• Evidence base: Supported by preclinical and small-scale human studies; large-scale Western trials are lacking.
• Safety: Reported as well tolerated in limited studies, with no significant adverse effects noted, but comprehensive long-term safety data is unavailable.

Disclaimer

This material is provided for educational purposes only and summarizes published research on Pinealon.
It is not medical advice. Pinealon is experimental, not FDA-approved, and should not be viewed as a therapy for medical use.

This peptide is for research use only.